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IMPORTANT SYLLABUS FOR GPAT

 MOST IMPORTANT TOPICS IN GPAT

 

 

Pharmacology

22 Questions

 

 

Drug classification, Mechanism of action, Adverse effect- related with a name like Gray baby syndrome, etc  (Mostly you can follow: Anticancer, Antibiotics, Antifungal, Antiprotozoal, Diuretics, CNS depression, Antihistamines, Cardiovascular Drugs)

 

Medicinal Chemistry

10 Questions

 

SAR (Mostly Diuretics, BZDs, Morphin); Drug classification of  (Sedative hypnotics, Antibiotics, Antimalarial, Morphin, Antihistaminic); Synthesis ( Thiazide Diuretics, Phenothiazine, Quinine, BZDS, Antihistaminic ) IUPAC Name of Steroidal drugs.

 

Organic Chemistry 

8 Questions

 

IUPAC (Bicyclo, Spiro, and heterocyclic compounds), Optical and Geometrical isomerism. R, S / E Z, /Conformational isomerism, Newman and sawhorse projection, Name reaction ( Diels- Alder Reaction, Knoevenagel, Aldol Condensation, Baeyer-Villiger, Claisen Condensation, Cannizzaro reaction, Reimer Tiemann, Pericyclic reaction.

 

Pharmacognosy 

7 Questions

 

Chemical test (glycoside and alkaloids most important), Microscopic Character (Senna, Digitalis, Aloe, Clove, Cardamom, Cinnamon, Belladonna, Vinca); Biosynthesis Pathway, Tissue Culture,   Sources of Drugs; Classification of Drugs; Chemical constituents & use of Ergot, Nux Vomica, Opium, Belladonna, Clove, Kurchi, Vasaka, Digitalis, Senna, Aloe, Clove, Cardamom, Cassia, Cinnamon, Ispaghula, Asafoetida, Peru & Tolu balsam, Myrobalan, Arjuna, Pale &black catechu.

 

Jurisprudence

3 Questions

 

Pharmacy acts Years only, Drug Schedule, DTAB Members

 

Analytical Chemistry

6 Questions

 

Woodward-Fieser Rule, Lambert’s Law-Beer’s law, UV Absorption Band & shift, IR( Sampling technique, molecular vibration, Vibration range for different grs); NMR (No of signal calculation, Chemical shift), Mass Spectroscopy (types of peak,  use) Gas chromatography (Detectors, Use), HPLC ( Instrumentation, use); 

 

Pharmaceutics

16 Questions

 

Tablet ( Mostly Coating, instrument, and excipients),  Capsule, Parenterals, Rheology (Nonnewtonian’s flow) HLB Values, Surfactant, Carr’s index, Hausner ratio, Angle of repose, Emulsion, Fick’s law, Zeta Potentials, Preservatives, artificial sweetener  dose calculation sums elf-life and half-life, vol of distribution & plasma conc, rate of clearance, one and two-compartment model sums, AUC- Dose fraction -as i.v or oral; Bioavailability calculation.

 

Physical Chemistry

3 Questions

 

Chemical kinetics sums, Solution (molality, molarity , Normality and neutralization sums), Thermodynamics. Isotonic sums. 

 

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